Why CBD in a Vertical Spray?
NeuroDiol™ Vertical Spray delivery has 8 times better absorption of CBD then any oral product especially into the nervous system and brain! Absorption is also much faster such that effects can be felt in a little as 3-5 minutes after dosing using our NeuroDiol™ Vertical Spray. Therefore you can take a much smaller dose for the same effects. Due to the high vascularity in the nasal passage, the CBD goes right into the bloodstream and quickly to the brain where many conditions have been shown in studies to best benefit.
Oral absorption of CBD, on the other hand, is inconsistent and slow.
When you take CBD pills or swallowed drops through the stomach, the active ingredient must pass through your liver before being absorbed. This is called the first pass effect. One of the main jobs of the liver is to break up and metabolize anything we eat or drink. That slows down and diminishes orally administered CBD effects considerably, and requires much larger dosing. This is why NeuroDiol offers both Bullets and Vertical Sprays which both bypass the first pass effect. Try either of them once and you will be convinced it is much superior to oral CBD.
What about vaping and smoking CBD
NeuroDiol™ Vertical Spray is much safer than vaping or smoking, and much better absorbed than transdermal creams or patches.
Vaping and smoking CBD dabs is a rapid way to deliver CBD with bioavailability similar to nasal CBD (Ohlsson et al. 1984). Vaping and smoking, however, expose the lungs to other harmful fumes that may be associated with lung disease.
Besides the health considerations, you can only smoke or vape in certain locations, whereas you can keep your NeuroDiol™ Vertical Spray handy anywhere you need it!
Transdermal applications in creams such as NeuroDiol™ Topical Cream can be very good to get a local CBD effect on a muscle, nerve, skin or an injury but this is not the best for a systemic effect. It can be best in many cases to mix and match different delivery methods together such as the NeuroDiol™ Topical Cream used with the NeuroDiol™ Vertical Spray or the NeuroDiol™ 2500mg Tincture can be taken then the NeuroDiol™ Vertical Spray used for break through pain or anxiety. Or NeuroDiol™ Bullet can be taken for sleep but if you wake up in the middle of the night and wish to get a fast dose of CBD you can then take the NeuroDiol™ Vertical Spray. Consider some of the NeuroDiol™ Combo Packages we offer.
Supplement Facts
10-20 milliliter bottle- 1-4 mists in one or each nostril every 2-4 hours.
Amount Per bottle % Daily Value
Water soluble Ultra Nano
Full Spectrum Hemp (Organic) 250mg, 450mg
Terpenes: Limonene. *****
Myrcene, Linalool, Alpha & Beta Pinene *****
MCT (Organic) *****
Potassium Sorbate, Glycerine. *****
*Daily Value not established
NeuroDiol™ Vertical Spray comes in strengths 250mg (4.2mg per spray) & 450mg (6.7mg per spray)
Terpene Profile
Terpenes: These are the NON psychoactive components in cannabis. They are the fragrant essence of ALL essential oils! They give plants their unique smell and hold the healing benefits within the plants. Terpenes have been studied extensively and are at the forefront of interest of the pharmaceutical companies due to the unique and safe profile they can have. Terpenes that are specifically shown to reduce pain, are anti inflammatory and reduce anxiety have been incorporated into NeuroDiol™.* These terpenes also have been shown to improve CBD and other cannabinoids utilization and uptake into the brain.*
Myrcene (or β-myrcene) is a terpene that occurs often in highly fragrant plants and herbs such as mangoes, hops, bay laurel leaves, thyme, lemongrass, and basil. Myrcene is produced by numerous cannabis strains, and some rodent-model studies have suggested that it might lend sedative effects. Main effects are Anti-inflammatory, Analgesic (pain relief), Antibiotic, Mood Elevation and Antimutagenic (anti cancer).*
Another place you’ll find myrcene is in mangoes. Anecdotal evidence suggests that eating a ripe mango prior to consuming cannabis may accentuate or extend the effects of cannabinoids; some have suggested that this is due to the fruit’s concentrations of myrcene, which is naturally synergistic with CBD and allows cannabinoids to more easily bridge the blood-brain barrier.
Linalool is a naturally occurring terpene found in many flowers and spices including lavender and coriander. It gives off a complex yet delicate floral aroma, and while its effects are myriad, it is in particular one of the substances used most widely to reduce stress. Humans have inhaled the scent of certain plants, including many containing linalool, since ancient times to help lower stress levels, fight inflammation, and combat depression.* Linalool has been the subject of many studies, including a recent one in which scientists allowed lab rats to inhale linalool while exposing them to stressful conditions. It was reported that linalool returned elevated stress levels in the immune system to near-normal conditions. Linalool’s Effects and Benefits include anti-anxiety, Antidepressant, Mood Elevation, Anti-inflammatory, Anti-epileptic and Analgesic.*
Limonene is an aromatic cannabis terpene produced in the flower’s resin glands. In isolation, it’s commonly associated with fruity and citrus aromas. Inhalation of limonene vapor increases serotonin and dopamine levels in key regions of the brain that are associated with anxiety, depression, and OCD. Limonene’s potential therapeutic benefits have shown potential in the following applications: Elevated mood*, Stress relief*, Antifungal properties*, Antibacterial properties*, May help relieve heartburn and gastric reflux*, Improves absorption of other terpenes and chemicals by way of the skin, mucous membranes, and digestive tract*
There’s also promising evidence for limonene’s anti-tumor effects. In lab rodents, limonene inhibited the growth of skin and mammary tumors. These studies were followed up with a Phase I human clinical trial which found that limonene was somewhat effective at reducing breast cancer tumor growth for nearly a year.* Later studies found that daily limonene supplementation for 2-6 weeks silenced a protein that promotes breast cancer tumor growth, suggesting that daily limonene consumption may inhibit the growth and spread of breast tumors.* Additional reports have revealed benefits of limonene in laboratory models of lung cancer and brain cancer by causing tumor cell death.* But like limonene’s benefits in breast cancer, high doses are likely needed beyond what may be present in cannabis alone.
Alpha & Beta Pinene, as you might have guessed it, has a strong scent of pine. Commonly found in conifer trees, parsley, dill, basil, and rosemary, alpha-pinene is easy to detect. If a chemical profile of your cannabis strain is unavailable, just follow your nose. Popular strains with high alpha-pinene levels include Jack Herer, Blue Dream, and OG Kush. This powerful aromatic molecule doesn’t just smell great, it also contains many medicinal benefits.
Anti-Inflammatory
A study in 2012 showed that alpha-pinene was a potent anti-inflammatory agent against Acute Pancreatitis, an inflammatory disease with an unknown cause. A study in 2011 showed that alpha-pinene, along with all the different cannabinoids and terpenes found in cannabis, interact synergistically and amplify anti-inflammatory activity. These results show that alpha-pinene is helpful in inflammation management for diseases such as arthritis, Crohn’s, and multiple sclerosis.
Anti-Microbial
Both alpha-pinene and beta-pinene proved to be effective antimicrobial agents against bacterial and fungal cells. In 2011, alpha-pinene was tested as a potent treatment against a bronchitis virus that was previously hard to treat since antibiotics don’t work on viruses. Although not effective against all bacteria and viruses, alpha-pinene protects against a wide range of these infectious diseases. More studies need to be performed to assess the effectiveness of alpha-pinene on all bacteria.
Bronchodilator
Although one study claims that alpha-pinene exposure can cause upper respiratory irritation, the benefits far outweigh mild negative symptoms. In a 2011 study, alpha-pinene showed promise as a bronchodilator by opening up the upper respiratory tract (at low exposure levels), which can be helpful for people with asthma.
Memory
We’ve all heard of the forgetful stoner stereotype. The cannabinoid tetrahydrocannabinol (THC) plays a part in decreasing short-term memory attention. The alpha-pinene terpene, however, has been shown to counteract these memory impairing effects. Alpha-pinene plays a strong role in inhibiting acetylcholinesterase activity in the brain, which helps you retain memories more efficiently.
Citrus Clementina
Pungent, refreshing, and sweet, Clementine terpenes supplies a variety of benefits, including its cleansing properties. Clementine’s citrus scent can improve and uplift your mood.
Clementine is a natural hybrid of mandarin and sweet orange. Clementine may boost the immune system, support metabolic function, and support gastrointestinal health.* It can help relieve occasional heartburn and indigestion.* Clementine terpene is versatile as it may aid healthy respiratory function as well.*
Aromatic benefits of Clementine include elevation of mood and positive emotions. Citrus oils, including Clementine, can also help you feel more invigorated and less anxious. Not only does diffusing Clementine lift your emotions, it also purifies and cleanses the air. Enhance your general health by adding Clementine to your wellness routine.
Disclosures, COA's & Lab Testing
WARNINGS: Although safe for children, this product should be kept out of the reach of children. Do not use if the packaging is open or damaged. As with any nutrient, if you are pregnant or breastfeeding, seek the advice of a health care provider before using this product.
Please know that this product can be taken safely by mouth. It is a dietary supplement in accordance with current FDA guidelines.
FOOD AND DRUG ADMINISTRATION (FDA) DISCLOSURE
*THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE.
Disclaimer: These statements have not been evaluated by the FDA. This product is a Federal Food, Drug, and Cosmetic Act compliant combination of naturally derived FDA GRAS (Generally regarded As Safe) herbal, nutraceutical, vitamins, minerals and amino acids products legally sold in the USA. In accordance with FDA regulations, with oral use it is a dietary supplement as defined by section 201(ff) of the Act, 21 U.S.C. § 321(ff). MitoZen’s product line is a naturally derived FDA GRAS (Generally regarded As Safe) mineral, herbal, vitamins and nutraceutical products which can be legally sold in the USA. ABC’s products are not a drug as defined in section 201(g)(1) of the Act, 21 U.S.C. § 321(g)(1). MitoZen’s products are not intended to affect the structure or function of the body and is not intended for use in the diagnosis, cure, mitigation, treatment or prevention of disease in man. Any nutritional suggestions and research regarding this product are provided for informational purposes only, and are not intended to diagnose, treat, cure or prevent disease nor should any information provided be used as a substitute for sound medical advice. This product is not for use by or sale to persons under the age of 18. This product should be used only as directed on the label. It should not be used if you are pregnant or nursing. Consult with a physician before use, if you have a serious medical condition or use prescription medications. A Doctor’s advice should be sought before using this and any supplemental dietary product. All trademarks and copyrights are the property of their respective owners, and are not affiliated with nor do they endorse this product. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. By using this site you agree to follow the Privacy Policy and Terms & Conditions printed on this site. Void Where Prohibited By Law.
COA’s and Lab Testing