Supplement Facts
Supplement Facts
Supplement Facts: NAD+Max™ Ultra
Serving size: 10ml Amount Per Serving/%Daily
Pure NAD+ Nicotinamide Adenine Dinucleotide 250mg/***
NR (Nicotinamide Riboside) 125mg/***
Methylene Blue *****
Proprietary Blend: Fisetin
*****
Lutein, Quercetin
*****
Resveratrol *****
Stevia, Natural Berry Flavor *****
Trimethyl Glycine (TMG) *****
Organic Sunflower Lecithin *****
SRT Polysaccharide Complex. *****
*Daily Value not established
Serving size: 5ml Amount Per Serving/%Daily
Pure NAD+ Nicotinamide Adenine Dinucleotide 250mg/***
NR (Nicotinamide Riboside) 125mg/***
Methylene Blue *****
Proprietary Blend: Fisetin
*****
Lutein, Quercetin,
*****
Resveratrol *****
Stevia, Natural Berry Flavor *****
Trimethyl Glycine (TMG) *****
Organic Sunflower Lecithin *****
SRT Polysaccharide Complex. *****
*Daily Value not established
Safety: Because of the potential risk of Serotonin Syndrome (a life-threatening condition) do not take this product if you are taking any product with SSRIs, SNRIs, or drugs that increase serotonin levels. MDMA, MDA, Ayahuasca, and psilocybin increase serotonin or have MAO-I properties similar. Avoid these substances stacked together.
Neuroprotective Efficacy of Methylene Blue in Ischemic Stroke: An MRI Study
Facts: NeuroNAD™ Vertical Spray
20 milliliters bottle / Bulk Bottle 120ml
Contains 60 veils of mist per 20ml bottle
Proprietary Blend
__________________________________________________
Pure NAD+ Nicotinamide Adenine Dinucleotide 2g/ml
Bio Ocean minerals *mg/ml
Terpenes: Eucalyptol. *mg/ml
Saline *mg/ml
GelTech *mg/ml
Natural Preservative *mg/ml
*Daily Value not established
Tips and Tricks
Tips and Tricks
See Fast Track Fast for an NAD+ Loading phase with NAD+Max.

NADMax+Ultra and NeuroNAD™ Vertical Spray can be taken together for an even more potent NAD+ replenishment program. The Heart and Brain and the most sensitive to low NAD+ levels. These two routes are the most superior routes next to IVs which costs between $500-1500 per IV and the IVs last 5-8 hours each.
NAD+Max™ Ultra can be taken anytime and
NeuroNAD™ Vertical Spray should be taken during the daytime 1-4 times a day for an effective boost into the brain where it is most needed!
NAD+Max Refuel dosage is designed for the use of both the
NAD+Max™ Bullet &
NeuroNAD™Vertical Spray. Building NAD+ along with fasting is also a great way to clean up cellular senescence!
Dosage:
I often have my patients do the following 90-day protocol:
- 2-5 consecutive days a week take NAD+Max™ Ultra in the morning upon waking. (Best if practicing intermittent fasting & skipping breakfast, but not necessary) .
- Use NeuroNAD™ Vertical Spray 2-3 times a day using 2 veils of mist. (The Vertical Spray can also be done fasting or feeding)
- Lucitol can be taken on 1-2 days following NAD+ administration to assist in clearing senescent cells.
Research on NAD+
Research on NAD+

Dr. John Lieurance with Dr. Mestayer at the 2015 NAD+ Summit. Dr. Mestayer is considered the leading authority in the USA on intravenous NAD infusions.
What is NAD?
Nicotinamide Adenine Dinucleotide (NAD) is a metabolic co-enzyme that structures, repairs, and is an essential component of energy production (mitochondrial function); heavily involved in DNA repair and cell repair; responsible for turning certain genes on and off; and is essential for maintaining neurotransmitter levels, for the proper functioning of the brain.
Why Is it Important?
NAD+ is essential to the creation of energy in the body and the regulation of pivotal cellular processes. Here’s why it’s so important, how it was discovered, and how you can get more of it.
NAD+, or nicotinamide adenine dinucleotide, is a critical coenzyme found in every cell in your body, and it’s involved in hundreds of metabolic processes. But NAD+ levels decline with age. NAD+ has two general sets of reactions in the human body: helping turn nutrients into energy as a key player in metabolism and working as a helper molecule for proteins that regulate other cellular functions. These processes are incredibly important.
How NAD+ Is Powerful
Open any biology textbook and you’ll learn about NAD+, which stands for nicotinamide adenine dinucleotide. It’s a critical coenzyme found in every cell in your body that’s involved in hundreds of metabolic processes like cellular energy and mitochondrial health. NAD+ is hard at work in the cells of humans and other mammals, yeast and bacteria, and even plants.
Scientists have known about NAD+ since it was first discovered in 1906, and since then our understanding of its importance has continued to evolve. For example, the NAD+ precursor niacin played a role in mitigating pellagra, a fatal disease that plagued the American south in the 1900s. Scientists at the time identified that milk and yeast, which both contain NAD+ precursors, alleviated symptoms. Over time scientists have identified several NAD+ precursors — including nicotinic acid, nicotinamide, and nicotinamide riboside, among others — which make use of natural pathways that lead to NAD+. Think of NAD+ precursors as different routes you can take to get to a destination. All the pathways get you to the same place but by different modes of transportation.
Recently, NAD+ has become a prized molecule in scientific research because of its central role in biological functions. The scientific community has been researching how NAD+ relates to notable benefits in animals that continue to inspire researchers to translate these findings to humans. So how exactly does NAD+ play such an important role? In short, it’s a coenzyme or “helper” molecule, binding to other enzymes to help cause reactions on the molecular level. But the body doesn’t have an endless supply of NAD+. It declines with age.
But the body doesn’t have an endless supply of NAD+. It declines with age. The history of NAD+ research, and its recent establishment in the science community, has opened the floodgates for scientists to investigate maintaining NAD+ levels and getting more NAD+.
What is the History of NAD+?
NAD+ was first identified by Sir Arthur Harden and William John Young in 1906 when the two aimed to better understand fermentation — in which yeast metabolizes sugar and creates alcohol and CO2. It took nearly 20 years for more NAD+ recognition when Harden shared the 1929 Nobel Prize in Chemistry with Hans von Euler-Chelpin for their work on fermentation. Euler-Chelpin identified that the structure of NAD+ is made up of two nucleotides, the building blocks for nucleic acids, which make up DNA. The finding that fermentation, a metabolic process, relied on NAD+ foreshadowed what we now know about NAD+ playing a critical role in metabolic processes in humans.
Euler-Chelpin, in his 1930 Nobel Prize speech, referred to NAD+ as cozymase, what it was once called, touting its vitality. “The reason for our doing so much work on the purification and determination of the constitution of this substance,” he said, “is that cozymase is one of the most widespread and biologically most important activators within the plant and animal world.”
Otto Heinrich Warburg — known for “the Warburg effect” — pushed the science forward in the 1930s, with research further explaining NAD+ playing a role in metabolic reactions. In 1931, the chemists Conrad A. Elvehjem and C.K. Koehn identified that nicotinic acid, a precursor to NAD+, was the mitigating factor in pellagra. The United States Public Health Service Doctor Joseph Goldberger had previously identified that the fatal disease was connected to something missing in the diet, which he then called PPF for “pellagra preventive factor.” Goldberger died before the ultimate discovery that it was nicotinic acid, but his contributions led to the discovery, which also informed eventual legislation mandating the fortification of flours and rice on an international scale.
In the next decade, Arthur Kornberg, who later won the Nobel Prize for showing how DNA and RNA are formed, discovered NAD synthetase, the enzyme that makes NAD+. This research marked the beginning of understanding the building blocks of NAD+. In 1958, the scientist’s Jack Preiss and Philip Handler defined what’s now known as the Preiss-Handler pathway. The pathway shows how nicotinic acid — the same form of vitamin B3 that helped cure pellagra — becomes NAD+. This helped scientists further understand the role of NAD+ in the diet. Handler later earned the National Medal of Science from President Ronald Reagan, who cited Handler’s “outstanding contributions to biomedical research…furthering the state of American science.”
While scientists had now realized the importance of NAD+, they had yet to discover its intricate impact on a cellular level. Forthcoming technologies in scientific research combined with comprehensive recognition of the coenzyme’s importance ultimately encouraged scientists to continue studying the molecule.
The Nuance of NAD+
Our current understanding of the importance of NAD+ began in the 1960s. Using nuclear extracts from hen liver, French scientist Pierre Chambon identified a process called Poly ADP-ribosylation, where NAD+ is broken down into two parts, one of which (nicotinamide) gets recycled, while the other (ADP-ribose) meets up with a protein. This research formed the foundation of the field of PARPs, or poly (ADP-ribose) polymerases, a group of proteins that rely on NAD+ to function and perform cellular functions. PARPs are similar to another group of proteins called sirtuins in that they both only function in the presence of NAD+.
Scientists often refer to sirtuins as “guardians of the genome” for their role in regulating cellular homeostasis. Homeostasis involves keeping the cell in balance. Sirtuins are a group of proteins that were first discovered in the 1970s but their dependence on NAD+ wasn’t realized until the 1990s. MIT biologist Leonard Guarente identified that SIR2, a sirtuin in yeast, extended the life of the yeast only when it was activated by NAD+.
“Without NAD+, SIR2 does nothing. That was the critical finding on the arc of sirtuin biology,” Guarente said.
Knowing this created a clear link between sirtuins and metabolism. It also clued scientists in on crosstalk between biological functions, i.e., that metabolism is intricately related to other biological processes. Additionally, it inspired more research on a topic previously overlooked.
“There are maybe 12,000 papers on sirtuins now. At the time we discovered the NAD+ dependent deacetylase activity the number of papers was in the 100s,” Guarante’s said.
Humans get NAD+ from their diet via foods, however, NAD+ is not absorbed orally and must be taken as an IV or Nasal Spray such as with NeuroNAD™ Nasal Spray, historically.
Dr. Lieurance worked toward creating a better NAD+ delivery and shortly after pioneering Nasal Delivery in 2018, he began working on a way to make NAD+ stable in a suppository thus NeuroNAD™ Suppository was born after discovery. NeuroNAD™ Suppository combines ABC’s SRT™ Slow Release Technology along with Nano Lipospheric Technology NLT NAD+™. Both NeuroNAD™ products are a highly efficient way to boost NAD+ in the body and can be used together for maximum effect to raise levels.
Disclaimer, Disclosure and Lab Testing
Disclaimer, Disclosure and Lab Testing
WARNINGS: Although safe for children, this product should be kept out of the reach of children. Do not use it if the package is open or damaged. As with any nutrient, if you are pregnant or breastfeeding, seek the advice of a health care provider before using this product.
Please know that this product can be taken safely by mouth. It is a dietary supplement by current FDA guidelines.
FOOD AND DRUG ADMINISTRATION (FDA) DISCLOSURE
*THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE.
Disclaimer: These statements have not been evaluated by the FDA. This product is a Federal Food, Drug, and Cosmetic Act-compliant combination of naturally derived FDA GRAS (Generally regarded As Safe) herbal, nutraceutical, vitamins, minerals, and amino acids products legally sold in the USA. By FDA regulations, oral use is a dietary supplement as defined by section 201(ff) of the Act, 21 U.S.C. § 321(ff). MitoZen’s product line is a naturally derived FDA GRAS (Generally regarded As Safe) mineral, herbal, vitamins, and nutraceutical products that can be legally sold in the USA. ABC’s products are not a drug as defined in section 201(g)(1) of the Act, 21 U.S.C. § 321(g)(1). MitoZen’s products are not intended to affect the structure or function of the body and are not intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease in man. Any nutritional suggestions and research regarding this product are provided for informational purposes only, and are not intended to diagnose, treat, cure, or prevent disease nor should any information provided be used as a substitute for sound medical advice. This product is not for use by or sale to persons under the age of 18. This product should be used only as directed on the label. It should not be used if you are pregnant or nursing. Consult with a physician before use, if you have a serious medical condition or use prescription medications. A Doctor’s advice should be sought before using this and any supplemental dietary product. All trademarks and copyrights are the property of their respective owners, and are not affiliated with nor do they endorse this product. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. By using this site you agree to follow the Privacy Policy and Terms & Conditions printed on this site. Void Where Prohibited By Law.
Reviews (5)
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Shipping & Delivery
During the hot summer months, we recommend taking advantage of the cold shipping option to ensure product stability upon arrival.
- Orders placed on a Thursday or Friday and requiring cold shipping will not ship until the following Monday.
- Orders placed over the weekend will not be shipped until Monday.
Beth (verified owner) –
So far enjoying the benefits
sharon mclellan (verified owner) –
would not live without this supplement
Conrad Spangler (verified owner) –
Seems to be fine
Florida A. (verified owner) –
Great product
Adele Azretali (verified owner) –
💪🏽