NeuroDiol™ Deep Penetrating Blue Cream 50ml bottle is a way to deliver the amazing benefits of CBD directly to an area of your body such as a sore muscle, inflamed nerve, injured or arthritis joints, any injury and even various skin conditions. NeuroDiol™ Deep Penetrating Blue Cream delivers NeuroDiol™ through the skin with the use of deep-penetrating, ultra-absorbable creams that have a unique, proprietary formulated base that has revolutionized not only this mode of delivery, but also the ability to obtain nutrients in a far more efficacious method.  These creams are a result of combining natural ingredients with a non-irritating, rapidly absorbable, Antioxidant Base, Cannabinoids, Terpenes and Essential Oils. NeuroDiol™ Deep Penetrating Blue Cream is an IMMEDIATE solution to delivering the necessary CBD, Essential Oils & Terpenes to specific body areas with absorption in minutes.

We have worked hard to source the most potent plants in order to make our whole plant full spectrum hemp extraction. Numerous studies support the full spectrum hemp extraction over the isolated CBD products for effectiveness. Besides the natural terpenes maintained through careful processing, NeuroDiol™ Deep Penetrating Blue Cream has an added terpene profile which makes it so advanced to support absorption and effectiveness of the CBD and other cannabinoids. Terpenes found in cannabis and hemp have been studied by the medical establishment for their healing powers and synergistic effects that are called the entourage effect. This is the effect in your body through various combinations of the cannabinoids along with these terpenes.

NeuroDiol™ Deep Penetrating Blue Cream is made from organic hemp grown in a high altitude farm on the big island of Hawaii where the rich volcanic soil is rich in minerals. The strain used in this product contains a super high CBD levels and the legal amount of THC along with the rich family of cannabinoids and terpenes normally contained in these special hemp plants grown with love and kindness. Please consult your healthcare provider regarding use and dosage of this product.

NeuroDiol™ Deep Penetrating Blue Cream, 50ml bottle contains 2500mg CBD from Full Spectrum Hemp.

Testimonials

“I’m one of those guys who often takes oral supplements and notices next to nothing. That’s not uncommon. Digestion, pass through the liver, the acidic nature of the stomach and a host of other factors can keep you from properly absorbing precious molecules. But when I tried Dr. Lieurance’s nasal sprays and suppositories I noticed them almost immediately. I have now used them successfully for jet lag, inflammation and enhanced sleep and I’m completely enamored: these things are the real deal – and a valuable arsenal to any health hacker’s toolkit.”

Ben Greenfield

Supplement Facts

50ml bottle-  Apply 1-2 dime size amounts and massage into skin.           

Amount Per bottle                                                    % Daily Value

Full Spectrum Hemp Extract (Organic)                  2500 mg

Terpene profile: Alpha Phellandrene, Linalool       *****

Alpha/Beta Pinene, Lemonene, Myrcene               *****

Hemp Seed Oil (Organic)                                         *****

Essential Oils: Ylang Ylang, Blue Tansy,               *****

Roman Chamomile, Peppermint,                            *****

Camphor, Copaiba, Boswellia                                 *****

*Daily Value not established

Research on CBD

CBD research under review:
Many studies on the impact of CBD, Hemp, Terpenes and cannabis historically have  employed small sample sizes, which limits the data researchers can gather and the conclusions they can draw from it. As the volume of these studies grows, though larger studies there will be more data to conduct review studies on the effects and efficacy of cannabis and its components, including CBD and Terpenes.

Rather than conducting a new experiment, review studies collate and compare the results of previously published, peer-reviewed studies. This allows authors to work with what is effectively a larger data set and more confidently answer questions about the subject.

Transdermal Perfect Terpene Profile

Terpenes: These are the NON psychoactive components in cannabis. They are the fragrant essence of ALL essential oils! They give plants their unique smell and they also hold the healing benefits within the plants. Terpenes have been studied extensively and they are at the forefront of interest of the pharmaceutical companies due to the unique and safe profile they can have. Terpenes that are specifically shown to reduce pain, are anti inflammatory and reduce anxiety have been incorporated into NeuroDiol™.* These terpenes also have been shown to improve CBD and other cannabinoids utilization and uptake into the brain.*

Myrcene: is a terpene that occurs often in highly fragrant plants and herbs such as mangoes, hops, bay laurel leaves, thyme, lemongrass, and basil. Myrcene is produced by numerous cannabis strains, and some rodent-model studies have suggested that it might lend sedative effects. Main effects are Anti-inflammatory, Analgesic (pain relief), Antibiotic and Mood Elevation.*

Another place you’ll find myrcene is in mangoes. Anecdotal evidence suggests that eating a ripe mango prior to consuming cannabis may accentuate or extend the effects of cannabinoids; some have suggested that this is due to the fruit’s concentrations of myrcene, which is naturally synergistic with CBD and allows cannabinoids to more easily bridge the blood-brain barrier.

Limonene: is an aromatic cannabis terpene produced in the flower’s resin glands. In isolation, it’s commonly associated with fruity and citrus aromas. Inhalation of limonene vapor increases serotonin and dopamine levels in key regions of the brain that are associated with anxiety, depression, and OCD. Limonene’s potential therapeutic benefits have shown potential in the following applications: Elevated mood*, Stress relief*, Antifungal properties*, Antibacterial properties*, May help relieve heartburn and gastric reflux*, Improves absorption of other terpenes and chemicals by way of the skin, mucous membranes, and digestive tract* (Ref)

Alpha & Beta Pinene, as you might have guess it, has a strong scent of pine. Commonly found in conifer trees, parsley, dill, basil, and rosemary, alpha-pinene is easy to detect.

A study in 2012 showed that alpha-pinene was a potent anti-inflammatory agent against Acute Pancreatitis, an inflammatory disease with an unknown cause. A study in 2011 showed that alpha-pinene, along with all the different cannabinoids and terpenes found in cannabis, interact synergistically and amplify anti-inflammatory activity. These results show that alpha-pinene support lower inflammation management for diseases such as arthritis, Crohn’s, and multiple sclerosis.*

Both alpha-pinene and beta-pinene proved to be effective antimicrobial agents against bacterial and fungal cells. In 2011, alpha-pinene was tested as a potent treatment against a bronchitis virus that was previously hard to treat since antibiotics don’t work on viruses. Although not effective against all bacteria and viruses, alpha-pinene was shown in research to supports the immune system a wide range of these infectious diseases. More studies need to be performed to assess the effectiveness of alpha-pinene on all bacteria. (Ref)

Bronchodilator: In a 2011 study, alpha-pinene showed promise as a bronchodilator by opening up the upper respiratory tract (at low exposure levels) which can be helpful for people with asthma.

Memory: We’ve all heard of the forgetful stoner stereotype. The cannabinoid tetrahydrocannabinol (THC) plays a part in decreasing short-term memory attention. The alpha-pinene terpene, however, has been shown to counteract these memory impairing effects. Alpha-pinene plays a strong role in inhibiting acetylcholinesterase activity in the brain, which helps you retain memories more efficiently. (Ref)

Alpha Phellandrene: This terpene smells herbaceous, citrusy, minty, peppery, and a little woodsy. The next time you smell mint leaves or a lavender candle, appreciate the Alpha Phellandrene terpene smell!

Antidepressive & Analgesic Actions of limonene, α-Phellandrene, and in a Neuropathic Pain Model (Ref)

Alpha–phellandrene significantly inhibited the production of the pro-inflammatory cytokines TNF-α and IL-6. Alpha–phellandrene Promotes Immune Responses in Normal Mice Through Enhancing Macrophage Phagocytosis and Natural Killer Cell Activities.  (Ref)

Alpha–phellandrene has modulating effect on neutrophil migration and mast cell degranulation processes. (Ref)

Boswellia: or Indian frankincense, is a resin herbal extract from the boswellia tree, which natural medicine practices have used for centuries. Its anti-inflammatory effects mean that it may help with inflammatory conditions, such as rheumatoid arthritis, inflammatory bowel disease, and asthma. We included this amazing extract into our products due to all of the positive healing properties

Linalool: is a naturally occurring terpene found in many flowers and spices including lavender and coriander. It gives off a complex yet delicate floral aroma, and while its effects are myriad, it is in particular one of the substances used most widely to reduce stress. Humans have inhaled the scent of certain plants, including many containing linalool, since ancient times to help lower stress levels, fight inflammation, and combat depression.* Linalool has been the subject of many studies, including a recent one in which scientists allowed lab rats to inhale linalool while exposing them to stressful conditions. It was reported that linalool returned elevated stress levels in the immune system to near-normal conditions. Linalool’s Effects and Benefits include anti-anxiety, Antidepressant, Mood Elevation, Anti-inflammatory, Anti-epileptic and Analgesic.* (Ref)

Dosage and Use

Dosage and Storage Instructions:  To start, we recommend 1-2 dime size amounts massaged into the skin and or body area which you would like to apply it to such as a sore muscle, nerves or a joint.  Store in cool dry area.

When you take CBD pills or swallowed drops through the stomach, the active ingredient must pass through your liver before being absorbed. This is called the first pass effect. One of the main jobs of the liver is to break up and metabolize anything we eat or drink.  That slows down and diminishes orally administered CBD effects considerably, and requires much larger dosing. This is why NeuroDiol™ offers Deep Penetrating Cream, Super dose Suppository and a Fast Acting Nasal Sprays which all bypass the first pass effect. Try either of them once and you will be convinced it is much superior to oral CBD or Hemp. Although our NeuroDiol™ Tinture also works amazing these optional delivery methods all have there unique benefits.

NeuroDiol™ Topical Cream is much safer than vaping or smoking, and much better absorbed locally for getting CBD to specific areas that need it.

For a systemic effect vaping and smoking CBD is a rapid way to deliver CBD with bioavailability similar to NeuroDiol™ Nasal Spray (Ohlsson et al. 1984). Vaping and smoking, however, expose the lungs to other harmful fumes that may be associated with lung disease.

Besides the health considerations, you can only smoke or vape in certain locations, whereas you can keep your NeuroDiol™ Topical Cream handy anywhere you need it and the same goes for the NeuroDiol™ Nasal Spray and Tincture!

Transdermal applications in creams such as NeuroDiol™ Topical Cream  can be very  good to get a local CBD effect on a muscle, nerve, skin or an injury but this is not the best for a systemic effect. It can be best in many cases to mix and match different delivery methods together such as the NeuroDiol™ Topical Cream used with the NeuroDiol™ Nasal Spray or the NeuroDiol™ 2500mg Tincture can be taken then the NeuroDiol™ Nasal Spray used for break through pain or anxiety. Or NeuroDiol™  Suppository can be taken for sleep but if you wake up in the middle of the night and wish to get a fast dose of CBD you can then take the NeuroDiol™ Nasal Spray. Consider some of the NeuroDiol™ Combo Packages we offer.

Disclosures & Analytics

GlutaGenic does not sell or distribute any products that are in violation of the United States Controlled Substances Act (USA CDA). The company does sell and distribute hemp-based products.

FOOD AND DRUG ADMINISTRATION (FDA) DISCLOSURE

The statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent disease or medical conditions. The products and information found on GlutaGenic.com are not intended to replace professional medical advice or treatment. Individual results may vary. GlutaGenic urges you to seek the advice of a qualified professional for any health concern, and to share with your provider any information pertaining to your health and well-being, including the use of supplemental nutrition. We try our best not to make mistakes; however, if typographical errors appear in our site, we cannot be held responsible. All information presented here is not meant as a substitute for or alternative to information from healthcare practitioners. Please consult your healthcare professional about potential interactions or other complications before using any product. The Federal Food, Drug, and Cosmetic Act require this notice. COA’s and Lab Testing