“I’m one of those guys who often takes oral supplements and notices next to nothing. That’s not uncommon. Digestion, pass through the liver, and the acidic nature of the stomach and a host of other factors can keep you from properly absorbing precious molecules. But when I tried Dr. Lieurance’s products, I noticed them almost immediately. I have now used them successfully for jet lag, inflammation, and enhanced sleep and I’m completely enamored: these things are the real deal – and a valuable arsenal to any health hacker’s toolkit.”
Ben Greenfield
Research on Melatonin
Research on Melatonin
Melatonin is 4x more potent, as a free radical scavenger than antioxidants such as (vitamin C or E)! Plus for va ery molecule of melatonin 10 free radicals are scavenged. This is a massive antioxidant load that Melatonin takes on! Melatonin doesn’t stop there it also transforms free radicals into “melatonin metabolites” which also act as free radical scavengers. This process is referred to as “the free radical scavenging cascade”. No other known antioxidant is capable of exerting this remarkably double effect as an antioxidant!
All other major antioxidants in the body, such as glutathione (GSH), superoxide dismutase (SOD), and catalase (CAT) are activated by Melatonin! Sandman provides 200mg of absorbable Melatonin that is time released. Studies show oral Melatonin is only 2.5% absorbed! Sandman delivers unparalleled and essential brain and body protection and anti-aging effects.
“We explore the mechanism of melatonin that is associated with the role of stress as a key factor to precipitate depression and as a factor altering neurogenesis, supporting the notion that melatonin possesses anti-stress and neurogenic actions. On the other hand, melatonin shows a pleiotropic character and it is a versatile and ubiquitous antioxidant molecule with low toxicity and high efficacy in reducing oxidative damage. Furthermore, melatonin has anti-inflammatory effects by regulation of multiple cellular pathways and properties to prevent excitotoxicity, among others.” (Ref)
There have been over 4,000 publications in peer review journals in the National Library of Medicine confirming melatonin, in super high physiologic dosages is safe and not toxic with dosages as high as 52,000 mg in animal models showing no toxicity. It has been shown in these studies to be the most powerful antioxidant our bodies use!
This video by Dr. Reiter is an excellent place to start with your journey to discover melatonin and how it may help you.
Below is Dr. Been’s Melatonin Presentation. Warning: It’s a very deep dive!
Dosage and Storage Instructions: Wash your hands thoroughly with soap and water. Keep the bullet in the refrigerator so it remains hard before removing the wrapper. Put on a finger cot or disposable glove, if desired (available at a pharmacy). Lubricate the bullet with a water-soluble lubricant such as K-Y Jelly or coconut oil, not petroleum jelly (Vaseline). If you do not have this lubricant, moisten your rectal area with cool tap water. Lie on your side with your lower leg straightened out and your upper leg bent forward toward your stomach. Lift the upper buttock to expose the rectal area. Insert the bullet, pointed end first, with your finger until it passes the muscular sphincter of the rectum, about ½ to 1 inch in infants and 1 inch in adults (If not inserted past this sphincter, the bullet may pop out). Hold buttocks together for a few seconds. Remain lying down for about 5 minutes to avoid having the bullet come out. Discard used materials and wash your hands thoroughly.
The suggested dosage is 1 (one) suppository daily. Depending on your daily schedule, it is recommended that you insert the bullet before bed.
You might need to become accustomed to the high melatonin dosing so start with 1/2 and work up to it. If you feel groggy go get in the sunlight in the morning as melatonin plus light, especially in the eyes you won’t be tired.
Supplement Facts: Sandman
Serving size: 1 Serving: 15
Amount Per Piece % Daily Value
L Glutathione 250mg
Melatonin 200mg
Magnolia / Hemp Extract. **/20mg
AP0-808 Probiotic Blend *****
SRT Polysaccharide Complex. *****
Full Spectrum Hemp Extract 20mg
Terpene Profile: Linalool, Myrcene *****
Essential Oils: Boswellia, Copaiba *****
Organic Palm Oil. *****
Our Technology
Our Technology
Many folks are uneasy with even mentioning rectal bullets until they realize how very powerful this approach can prove to be. For some navigating around this phobia could make the difference between health and sickness or enhanced performance for those biohackers!
There is a growing acknowledgment of the need to provide safer, more cost-effective treatments that can either reduce the need for pharmaceuticals (ie: drugs) and/or reduce their side effects. There is a mountain of research to demonstrate vitamins, extracts, nutrients, herbals, and nutraceuticals can do just that, if only they could be absorbed in such a manner as to allow greater therapeutic effect.
<h4>How do Rectal Bullets Work?</h4>
Everything, when administered orally, is absorbed from the gastrointestinal tract into the portal venous circulation and passes through the liver (first pass metabolism) where the process of metabolism or breakdown begins. Bullets, like intravenous (IV), intramuscular (IM), and transdermal methods of administration, bypass this “first pass” effect and are absorbed into the rectal veins without encountering liver metabolism. Fortunately, the rectum is filled with blood vessels that offer direct access to the body’s bloodstream. This allows for rapid access to the systemic circulation.
When nutrients are put into our special bullet base they are protected and delivered through Slow Release Technology along with the support of the probiotics APO-808. All Glutagenic’s™’s proprietary bullet base is formulated with ingredients that promote the movement of the active nutrients from the base to the rectum. This technology facilitates solubility and allows a compound that is usually insoluble in water (hydrophobic) to dissolve, and thus be absorbed. This is crucial for poorly absorbed compounds.
<strong>GlutaGenic’s bullets are easy to insert, non-irritating, rapid-melting, fully absorbed in 5-10 minutes, and you’ll not know it in there after insertion.</strong>
Terpene Profile
Terpene Profile
Terpenes: They are the fragrant essence of ALL essential oils! They give plants their unique smell and they also hold healing benefits within the plants. Terpenes have been studied extensively and they are at the forefront of interest for pharmaceutical companies due to the unique and safe profile they can have. Terpenes that are specifically shown to reduce pain, are anti-inflammatory, and reduce anxiety have been incorporated into Sandman™.* These terpenes also have been shown to improve CBD and other cannabinoids utilization and uptake into the brain.*
Myrcene (or β-myrcene)is a terpene that occurs often in highly fragrant plants and herbs such as mangoes, hops, bay laurel leaves, thyme, lemongrass, and basil. Myrcene is produced by numerous cannabis strains, and some rodent-model studies havehave suggested that it might lend sedative effects. The main effects are Anti-inflammatory, Analgesic (pain relief), Antibiotic, Mood Elevation, and Antimutagenic (anti-cancer).*
Another place you’ll find myrcene is in mangoes. Anecdotal evidence suggests that eating a ripe mango before consuming cannabis may accentuate or extend the effects of cannabinoids; some have suggested that this is due to the fruit’s concentrations of myrcene, which is naturally synergistic with CBD and allows cannabinoids to more easily bridge the blood-brain barrier
Boswellia, or Indian frankincense, is a resin herbal extract from the Boswellia tree, which natural medicine practices have used for centuries. Its anti-inflammatory effects mean that it may help with inflammatory conditions, such as rheumatoid arthritis, inflammatory bowel disease, and asthma. We included this amazing extract in our products, due to all of its positive healing properties.
Linalool is a naturally occurring terpene found in many flowers and spices including lavender and coriander. It gives off a complex yet delicate floral aroma, and while its effects are myriad, it is in particular one of the substances used most widely to reduce stress. Humans have inhaled the scent of certain plants, including many containing linalools, since ancient times to help lower stress levels, fight inflammation, and combat depression.* Linalool has been the subject of many studies, including a recent one in which scientists allowed lab rats to inhale linalool while exposing them to stressful conditions. It was reported that linalool returned elevated stress levels in the immune system to near-normal conditions. Linalool’s Effects and Benefits include anti-anxiety, Antidepressant, Mood Elevation, Anti-inflammatory, Anti-epileptic, and Analgesic.*
Disclosures and Disclaimers
Disclosures and Disclaimers
WARNINGS:Although safe for children, this product should be kept out of the reach of children. Do not use it if the package is open or damaged. As with any nutrient, if you are pregnant or breastfeeding, seek the advice of a health care provider before using this product.
This product can be taken safely by mouth. According to FDA regulations this product is considered a dietary supplement as defined by section 201(ff) of the Act, 21 U.S.C. § 321(ff).
FOOD AND DRUG ADMINISTRATION (FDA) DISCLOSURE
*THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE.
Disclaimer:These statements have not been evaluated by the FDA.In accordance with FDA regulations, this product can be taken orally, this product and is considered a dietary supplement as defined by section 201(ff) of the Act, 21 U.S.C. § 321(ff).This product is a Federal Food, Drug, and Cosmetic Act-compliant combination of naturally derived FDA GRAS (Generally regarded As Safe) herbal, nutraceutical, vitamins, minerals, and amino acids products legally sold in the USA. According to FDA regulations this product is considered a dietary supplement as defined by section 201(ff) of the Act, 21 U.S.C. § 321(ff). MitoZen PMA’s product line is a naturally derived FDA GRAS (Generally regarded As Safe) mineral, herbal, vitamins, and nutraceutical products that can be legally sold in the USA. MitoZen PMA products are not a drug as defined in section 201(g)(1) of the Act, 21 U.S.C. § 321(g)(1). MitoZen’s products are not intended to affect the structure or function of the body and are not intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease in man. Any nutritional suggestions and research regarding this product are provided for informational purposes only, and are not intended to diagnose, treat, cure, or prevent disease nor should any information provided be used as a substitute for sound medical advice. This product is not for use by or sale to persons under the age of 18. This product should be used only as directed on the label. It should not be used if you are pregnant or nursing. Consult with a physician before use, if you have a serious medical condition or use prescription medications. A Doctor’s advice should be sought before using this and any supplemental dietary product. All trademarks and copyrights are the property of their respective owners, and are not affiliated with nor do they endorse this product. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. By using this site you agree to follow the Privacy Policy and Terms & Conditions printed on this site. Void Where Prohibited By Law.
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