SandMan Sol™ contains 250mg of Glutathione, 200mg of Melatonin, Terpene Blend (Limonene, boswellia), and our proprietary AP0-808™ probiotic strain. The body’s 2 most powerful anti-oxidant’s, Glutathione and Melatonin together!
This is the most advanced slow release over a 5-7 hour period, to support melatonin release, due to our proprietary slow release technology using SRT ™ Polysaccharide Complex.
This product utilizes a unique approach to health and healing using super high physiologic melatonin supplementation. See this article on Melatonin.
Testimonials
Testimonials
“I’m one of those guys who often takes oral supplements and notices next to nothing. That’s not uncommon. Digestion, pass through the liver, the acidic nature of the stomach and a host of other factors can keep you from properly absorbing precious molecules. But when I tried Dr. Lieurance’s nasal sprays and suppositories, I noticed them almost immediately. I have now used them successfully for jet lag, inflammation and enhanced sleep and I’m completely enamored: these things are the real deal – and a valuable arsenal to any health hacker’s toolkit.”
Ben Greenfield
Research on Melatonin
Research on Melatonin
Melatonin is 4x more potent, as a free radical scavenger, than antioxidants such as (vitamin C or E)! Plus, for very molecule of melatonin, 10 free radicals are scavenged. This is a massive antioxidant load that Melatonin takes on! Melatonin doesn’t stop there. It also transforms free radicals to “melatonin metabolites” which also act as free radical scavengers. This process is referred to as “the free radical scavenging cascade”. No other known antioxidant is capable of exerting this remarkably double effect as an antioxidant!
All other major antioxidants in the body, such as glutathione (GSH), superoxide dismutase (SOD), catalase (CAT) are activated by Melatonin! Sandman provides 200mg of absorbable Melatonin , which is time released. Studies show oral Melatonin is only 2.5% absorbed! Sandman delivers unparalleled essential brain and body protection, as well as anti-aging effects.
“We explore the mechanism of melatonin, which is associated with the role of stress as a key factor to precipitate depression, and as a factor altering neurogenesis. This supports the notion that melatonin possesses anti-stress and neurogenic actions. On the other hand, melatonin shows a pleiotropic character. It is a versatile and ubiquitous antioxidant molecule, with low toxicity and high efficacy in reducing oxidative damage. Furthermore, melatonin has anti-inflammatory effects by regulation of multiple cellular pathways and properties to prevent excitotoxicity, among others.” (Ref)
There have been over 4,000 publications in peer review journals in the National Library of Medicine, confirming melatonin, in super high physiologic dosages, is safe. With dosages as high as 52,000 mg in animal models, melatonin shows no toxicity. It has been shown in these studies to be the most powerful antioxidant our bodies use!
This video by Dr. Reiter is an excellent place to start with your own journey to discover melatonin and how it may help you.
Below is Dr. Been’s Melatonin Presentation. Warning: Its a very deep dive!
Dosage and Storage Instructions: Wash your hands thoroughly with soap and water. Keep the suppository in the refrigerator so it remains hard before removing the wrapper. Put on a finger cot or disposable glove, if desired (available at a pharmacy). Lubricate the suppository with a water soluble lubricant such as K-Y Jelly or coconut oil, not petroleum jelly (Vaseline). If you do not have this lubricant, moisten your rectal area with cool tap water. Lie on your side with your lower leg straightened out and your upper leg bent forward toward your stomach. Lift upper buttock to expose the rectal area. Insert the suppository, pointed end first, with your finger until it passes the muscular sphincter of the rectum, about ½ to 1 inch in infants and 1 inch in adults (If not inserted past this sphincter, the suppository may pop out). Hold buttocks together for a few seconds. Remain lying down for about 5 minutes to avoid having the suppository come out. Discard used materials and wash your hands thoroughly.
Suggested dosage is 1 (one) suppository daily. Depending on your daily schedule, it is recommended that you insert the suppository prior to bed. You might need to become accustomed to the high melatonin dosing, so start with 1/2 and work up to it. If you feel groggy, get into the sunlight in the morning. With melatonin plus light, especially in the eyes, you wont be tired.
Supplement Facts: Sandman
Serving size: 1 Servings: 15
Amount Per Piece % Daily Value
L Glutathione 250mg
Melatonin 200mg
AP0-808 Probiotic Blend *****
SRT Polysaccharide Complex. *****
Terpene Profile: Limonene *****
Essential Oils: Boswellia, Copaiba *****
Organic Palm Oil. *****
****Daily Value not established
Terpene Profile
Terpene Profile
Terpenes: These are the NON psychoactive components in cannabis. They are the fragrant essence of ALL essential oils! They give plants their unique smell, and they also hold the healing benefits within the plants. Terpenes have been studied extensively and are at the forefront of interest of the pharmaceutical companies, due to the unique and safe profile they can have. Terpenes which are specifically shown to reduce pain, are anti inflammatory and reduce anxiety, have been incorporated into Sandman™.* These terpenes also have been shown to improve CBD and other cannabinoids utilization and uptake into the brain.*
Boswellia, or Indian frankincense, is a resin herbal extract from the boswellia tree, which natural medicine practices have used for centuries. Its anti-inflammatory effects mean that it may help with inflammatory conditions, such as rheumatoid arthritis, inflammatory bowel disease, and asthma. We included this amazing extract into our products, due to all of the positive healing properties
Our Technology
Our Technology
Sustained-release technology in ABC’s suppositories, are of benefit due to increased bioavailability. ABC has found that the addition of SRT improved the bioavailability of glutathione by 30%, compared to the suppositories without SRT. These absorptions were improved enormously by the addition of a proprietary and natural polypeptide. Excellent prolonged absorption and high bioavailability were obtained, exhibiting both high plasma level and prolonged absorption. Our research shows that ABC’s preparations containing SRT may be superior in a rectal preparation with prolonged action, and giving a high plasma level compared to standard suppository bases without ABC’s SRT!
Why do we use probiotics in our suppositories?
APO-808 is a proprietary blend of probiotic strains that is unique to our suppository technology. ABC has discovered that certain bacteria strain combinations of probiotics can support the absorption and utilization, when combined with various ingredients. Probiotics are beneficial bacteria that exist in our large intestine, which is called the microbiome, and is exactly where the suppository is absorbed. Using probiotics via suppository, makes for a unique route of delivery, as it bypasses the acid in the stomach that normally destroys most probiotics taken orally. In addition, it has been clinically shown that oral probiotics may not even colonize your gut at all. Due to the need for the probiotics to be incorporated into the gut wall, research has shown we might be wasting our money taking most probiotics orally. ABC’s probiotic strains have been combined with our special suppository base, which consists of organic palm oil. This combination rests on the gut wall over a 5-8 hour period, to allow for the incorporation and colonization of the bacteria in the large intestines. Besides the unique delivery of the probiotics via suppository route, it has been scientifically shown that many nutrients are brought into the bloodstream by various strains of beneficial flora in your microbiome. The scientists at ABC have isolated various combination of flora, which work specifically with the nutrients it is combined with.
APO-808 is designed to work with Glutathione in particular to down regulate the inflammation through normalizing the gut microbiome, as well as allowing maximum absorption of Glutathione. The strains contained in the APO-808 Blend have been shown in the research to support a healthy brain and body.
Why Suppositories?
Why Suppositories?
Many folks are uneasy with even mentioning of rectal suppositories until they realize how very powerful this approach can prove to be. For some navigating around this phobia could make the difference between health and sickness or enhanced performance fort those biohackers!
There is a growing acknowledgement of the need to provide safer, more cost-effective treatments that can either reduce the need for pharmaceuticals (ie: drugs) and/or to reduce their side effects. There is a mountain of research to demonstrate vitamins, extracts, nutrients, herbals and nutraceuticals can do just that, if only they could be absorbed in such a manner as to allow greater therapeutic effect.
How do Rectal Suppositories Work?
Everything, when administered orally, is absorbed from the gastrointestinal tract into the portal venous circulation. It then passes through the liver (first pass metabolism) where the process of metabolism or breakdown begins. Suppositories, like intravenous (IV), intramuscular (IM), and transdermal methods of administration, bypass this “first pass” effect and are absorbed into the rectal veins without encountering liver metabolism. Fortunately, the rectum is filled with blood vessels that offer direct access into the body’s bloodstream. This allows for rapid access to systemic circulation.
When nutrients are put into our special suppository base they are protected and delivered through Slow Release Technology along with the support of the probiotics APO-808. All Glutagenic’s™’s proprietary suppository base is formulated with ingredients that promote the movement of the active nutrients from the base to the rectum.This technology facilitates solubility, and allows a compound that is usually insoluble in water (hydrophobic) to dissolve, and thus be absorbed. This is crucial for poorly absorbed compounds.
ABC’s suppositories are easy to insert, non-irritating, rapid-melting, fully absorbed in 5-10 minutes, and you’ll not know its in there after insertion.
Dosage and Storage
Dosage and Storage
Dosage and Storage Instructions: Wash your hands thoroughly with soap and water. Keep the suppository in the refrigerator so it remains hard before removing the wrapper. Put on a finger cot or disposable glove, if desired (available at a pharmacy). Lubricate the suppository with a water soluble lubricant such as K-Y Jelly or coconut oil, not petroleum jelly (Vaseline). If you do not have this lubricant, moisten your rectal area with cool tap water. Lie on your side with your lower leg straightened out and your upper leg bent forward toward your stomach. Lift upper buttock to expose the rectal area. Insert the suppository, pointed end first, with your finger until it passes the muscular sphincter of the rectum, about ½ to 1 inch in infants and 1 inch in adults (If not inserted past this sphincter, the suppository may pop out). Hold buttocks together for a few seconds. Remain lying down for about 5 minutes to avoid having the suppository come out. Discard used materials and wash your hands thoroughly.
Suggested dosage is 1 (one) suppository daily. The first time it might be best to start with 1/2 for the first 2 days to allow your body to adapt to the high melatonin levels. It can be normal at first to feel a bit drowsy especially with no sunlight entering your eyes. After a few days of dosing this usually dissipates. Depending on your daily schedule this can be taken day or night.
DO NOT DRIVE OR OPERATE MACHINERY AFTER CONSUMING THIS PRODUCT.
Product is not intended for oral usage but can be taken orally.
Store this product in a refrigerated climate. Keep this product away from sunlight. Please use the product within six months of purchase date for best results.
Disclaimers, Disclosures, COA's and Lab Testing
Disclaimers, Disclosures, COA's and Lab Testing
Advanced Biome Corp does not sell or distribute any products that are in violation of the United States Controlled Substances Act (USA CDA). The company does sell and distribute hemp-based products.
FOOD AND DRUG ADMINISTRATION (FDA) DISCLOSURE
The statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent disease or medical conditions. The products and information found on AdvancedBiomeCorp.com are not intended to replace professional medical advice or treatment. Individual results may vary. Advanced Biome Corp urges you to seek the advice of a qualified professional for any health concern, and to share with your provider any information pertaining to your health and well-being, including the use of supplemental nutrition. We try our best not to make mistakes; however, if typographical errors appear in our site, we cannot be held responsible. All information presented here is not meant as a substitute for, or alternative to, information from healthcare practitioners. Please consult your healthcare professional about potential interactions or other complications before using any product. The Federal Food, Drug, and Cosmetic Act require this notice.
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Shipping & Delivery
Cold Shipping
During the hot summer months, we recommend taking advantage of the cold shipping option to ensure product stability upon arrival.
Shipping Disclaimer
Orders placed on a Thursday or Friday and requiring cold shipping will not ship until the following Monday.
Orders placed over the weekend will not be shipped until Monday.
Spore Based Probiotics & Butyrate in a Suppository? What a great idea!
Butyrate is a short-chain fatty acid essential for optimal digestive health. Holistic health care advocates have been using butyrate in the form of an enema for many years throughout the U.S. Now we are able to offer the same effective strategy in the form of a suppository. There is evidence in the literature that supplementing with butyrate can support people with distal ulcerative colitis and inflammatory bowel conditions like Crohn’s disease.
The important function that butyrate serves in the digestive system is to reduce inflammation, however it has numerous other benefits. Butyrate is a byproduct of the digestive process that can strengthen colonic defenses, prevent re-uptake of toxins into the body, and increase intestinal barrier function. Since butyrate is found naturally in a healthy colon, suppository use can be a safe and effective route of delivery.
When butyrate levels in the digestive system are low, it can result in ulcerative colitis, Crohn’s, and for some without an IBD condition it can cause diarrhea. A butyrate suppository is used to help restore the levels of butyrate in the colon. Our sodium butyrate suppositories are made of the highest quality materials.
Purchase one GlutaStat™ and receive a bottle of GlutaStat™ NS at 20% off. Only good for 3 combo’s please. Folks find the GlutaStat best for nebulizing (please see you health care professional), and the GlutaStat™ NS is a more concentrated product, which can really reduce microbial growth in the nasal passages and sinus. The ingredients in GlutaStat™ have been shown to work against a broad spectrum of microbes. Consider adding a Nebulizer to your order!
CONSIDER A BULK GLUTASTAT's FOR LONGER PROTOCOLS OR FOR YOUR ENTIRE FAMILY TO USE.
PLEASE SCHEDULE A $69 VIRTUAL APPOINTMENT WITH OUR DOCTOR FOR A PRESCRIPTION IN ORDER TO PURCHASE A NEBULIZER OR IF YOU HAVE A NEED FOR DIRECTION WITH PRODUCT USE.
Lucitol Ultra™ is a product that was developed with much excitement and care, to make sure the blend was perfect. We spent many months working with various plant polyphenol's from the flavonoid group. Lucitol Ultra™ is designed to provide the cleanest and most complete absorption of these key nutrients. This all star line up of Fisetin (Read my article here) Resveratrol, Ginkgo B., EGCG, Lutein, Quercetin & Curcumin are all in the Lucitol Ultra™. Also see NADMax Ultra™. Fasting is also a great way to clean up cellular senescence! Lucitol Ultra™can be take safely during a fast, as well as after using NAD+ Products, to minimize senescent survivability. See Mito Fast Protocol here. Polyphenols such as Fisetin & Curcumin are poorly absorbed through oral ingestion. Liposomes offer a valuable means to receive the most potent and fullest potential of these nutrients.
NeuroDiol™ Suppository's are made using full spectrum hemp extract from an organic Hawaiian grown, high CBD strain. We added terpenes, our probiotic blend APO-19™ and (SRT™) slow release technology for the worlds finest Hemp Suppository line.
Rectal administration of CBD and other cannabinoids allows your body to absorb considerably more than orally? By bypassing the destructive acids in the stomach, digestive enzymes and liver filter the NeuroDiol™ gets into your bloodstream through the rectal wall.
NeuroDiol™ Suppository's are an excellent way to deliver CBD close to problem areas in the rectal region such as large intestines, prostate, vagina and uterus.
NeuroDiol™ comes in 50mg, 125mg, 300mg and 600mg per suppository options. 125mg and 300mg are our best sellers!
Contains 20mL of GlutaStat NS™ for IntraNasal Application.
Excellent for chronic sinusitis, bronchitis, and any upper respiratory disorders.*
Reduction of rhinorrhea, hyper lacrimation, sneezing, and bronchospasm.*
High potency formula results in sustained-release Glutathione for optimal blood levels.*
Anti-Microbial Herbal Extracts of Wild Crafted Oregano, Copaiba, Sage, Bay Leaves and Clove.*
Terpenes: Limonene, Eucalyptol, Geraniol
This product was designed to provide optimal support for upper respiratory tract (Sinus’/Lungs)*
Using GelTech™ Technology for higher absorption.
CONSIDER A BULK 120 ml Bottle of GLUTASTAT™ NS FOR LONGER PROTOCOLS OR FOR YOUR ENTIRE FAMILY TO USE.
For Nebulizing consider the GlutaStat™ 30ml product.
PLEASE SCHEDULE A $69 VIRTUAL APPOINTMENT WITH OUR DOCTOR FOR A PRESCRIPTION IN ORDER TO PURCHASE A NEBULIZER, OR IF YOU HAVE A NEED FOR DIRECTION WITH PRODUCT USE.
*Should be kept refrigerated to maintain full potency.
MethylMax™ is a revolutionary product containing the most advanced methylator's combined in one suppository product. We use the highest quality, top of the line ingredients, with a slow release technology & our APO-808 probiotic strain for maximum absorption. You will not find this comprehensive of an ingredient list anywhere.
Co-Designed by Dr. Daniel Pompa and Dr. John Lieurance, for maximum support for detoxification pathways and hormone detox, as well as brain and neurological support. Try one for yourself and feel the dramatic difference in both the methylation ingredients, along with superior suppository delivery, compared to other products. You'll know that we have created something very special with MethylMax™.
Each order of MethylMax™ contains 15 suppositories. Consult your health care practitioner before using this or any of MitoZen's product line.
Serene™ 30 ml bottle, is the newest and most exciting product at MitoZen. We have worked hard to source the most potent plants in order to make our whole plant full spectrum hemp extraction. NeuroHEMP™ is our UltraNano, Water Soluble, Full Spectrum Hemp Delivery System with rapid onset. Chicken flavor makes this taste great for your cat or dog. Product provides a full 25mg/mil. Add to your pets food or drink, or put into any toy to dose your pet. Numerous studies support the full spectrum hemp extraction over the isolated CBD products for effectiveness. Besides the natural terpenes maintained through careful processing, Serene™ has an added terpene profile which makes it advanced enough to support absorption and effectiveness of the CBD and other cannabinoids. Terpenes found in cannabis and hemp have been studied by the medical establishment for their healing powers, and synergistic effects, called the entourage effect. This is the effect in your body, through various combinations of the cannabinoids, along with these terpenes.
This product is made from organic hemp grown in a high altitude farm on the big island of Hawaii, where the volcanic soil is rich in minerals. The strain used in this product, contains super high CBD levels and the legal amount of THC, along with the rich family of cannabinoids and terpenes in these special hemp plants grown with love and kindness. Please consult your healthcare provider regarding use and dosage of this product.
After many years of development we bring you a home kit that actually works! Dr. John was sick for many years, and was able to discover the key aspects of a natural, non drug and non anti-biotic approach to CIRS, Chronic Lyme Disease and or CIRS or Chronic Inflammatory Response Syndrome. This syndrome was first described by Dr. Richie Shoemaker, who has pioneered many aspects of diagnosing and treating mold illness, and runs the website www.survivingmold.com
Lyme disease, Breast Implant Illness and Mold Illness both share a similar phenomena where toxins are not adequately cleared from the cell based on the exposure and or build up of these, primary fat soluble, toxins such as biotoxins from the bacteria, Borrelia burgdorferi and the mycotoxins from mold organisms.
Biotoxins are substances which are both toxic and have a biological origin. They come in many forms and can be produced by nearly every type of living organism: there are mycotoxins (made by fungi), zootoxins (made by animals) and phytotoxins (made by plants). See the biotin pathways and all the ways they can have negative effects on your health.
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