More research is needed to learn about the possible side effects of using corydalis supplements with other herbs, supplements, or medications. Talk to your healthcare provider before you start taking corydalis, especially if you are already taking other prescription or over-the-counter (OTC) medications, supplements, or products. There has not been enough safety and effectiveness research on corydalis use in certain groups of people who might be at risk for side effects. Children should not take corydalis. In addition, adults should steer clear if they are Pregnant or Breastfeeding or a history of seizures. Studies show it can be safe to take for at least 4 weeks and possibly longer however speak to to health care provider before taking it longer than one month. Consuming corydalis can have side effects. There is a risk of THP toxicity from corydalis supplements show in animal studies at over 475mg/kilogram of body weight. With an average body weight of an adult at 70 kilo that's 33 grams of the THP alkaloid and this product contains 100mg of THP. In high doses THP can cause sever liver stress (acute hepatitis), the symptoms of which are nausea, vomiting, pain in the abdomen, or fever. Ref So don't take high doses and Solace is meant for short term use of less then 4 weeks.