Supplement Fact
Dosage and Storage Instructions: Consider taking Lucitol™ during fasting programs or within feeding windows.
Supplement Ingredients:
Bullets Per Serving size: 1 Servings: 15 Amount Per Serving % Daily Value
Proprietary Blend:
Fisetin, Pterostilbene *****
Ginkgo B., EGCG, Lutein *****
Quercetin, Curcumin, Apocynin *****
Resveratrol *****
AP0-808 Probiotic Blend *****
SRT Polysaccharide Complex. *****
Terpene profile: Alpha Pinene. *****
Beta Pinene, Delta 3 Carene *****
Alpha Phellandrene. *****
Organic Palm Oil *****
****Daily Value not established****
Research
Some of the most exciting studies on these polyphenols in neurology, as well as (senolytic/autophagy) and to address microglial activation.
Read my article on Fisetin here. See the amazing studies on Fisetin
(Ref) and you will see why many are looking at this nutrients as the father of all anti aging substances. Take a close look at Micro Glial activation as well as Cellular senescence to fully appreciate
Lucitol™ (Ref).
Senescent cells accumulate with age! Senescent cells are cells that go into a permanent state of sleep like a zombie, and continue to consume energy and produce lots of oxidation! Senescent cells secrete pro-inflammatory chemicals form something scientists call SASP (senescence-associated secretory phenotype).
The SASP’s are thought to significantly contribute to aging! (Ref) Senolytics, which remove SASP’s, are a great strategy for promoting health and longevity.
Poor energy levels at a cellular level are a headwind for the body to properly clear out these zombie cells. Mitochondria, the power house of the cell, is a key component to this cellular energy. Both NAD+ as well as mitochondria health decline with age. Fisetin, Resveratrol, Ginkgo B., EGCG, Lutein, Quercetin & Curcumin are all heavily researched
. Also
Fasting is also a great way to clean up cellular senescence!
Freund, A., Orjalo, A. V., Desprez, P. Y., & Campisi, J. (2010). Inflammatory networks during cellular senescence: causes and consequences. Trends in molecular medicine, 16(5), 238-246.
[4] Coppé, J. P., Desprez, P. Y., Krtolica, A., & Campisi, J. (2010). The senescence-associated secretory phenotype: the dark side of tumor suppression. Annual review of pathology, 5, 99. Fisetin, like other
polyphenols such as
resveratrol, is a
sirtuin-activating compound, and has been shown in laboratory studies to extend the life of simple organisms like yeast, worms, and flies.
[1] Like the other compounds, it has also been shown to be reactive in many different arrays of biological activities, raising the possibility that any drug generated from fisetin would have too many side effects to be useful.
[1][2] Fisetin has shown anti-cancer activity in studies on cells and model animals conducted in laboratories, and appears to block the
PI3K/AKT/mTOR pathway.
In lab studies, it also has been shown to be an
anti-proliferative agent, interfering with the
cell cycle in several ways.
Fisetin, like some other
flavonoids, has been found in lab studies to be a
topoisomerase inhibitor, which may turn out to be a carcinogenic activity or an anti-cancer activity – further research is needed.
[6] Fisetin has been shown to be an effective
senolytic agent in wild-type mice, with effects of increased lifespan, reduced senescence markers in tissues, and reduced age-related pathologies.
[7] A clinical trial in the U.S. is currently underway as of October 2018 to show effectiveness in humans.
[8] In studies conducted on cells in a laboratory, fisetin inhibits the activity of several pro-inflammatory
cytokines, including
tumor necrosis factor alpha,
interleukin 6, and
Nuclear factor kappa B.
[5] It has also been shown in lab studies to upregulate
glutathione, an endogenous antioxidant.
[5][9] Fisetin also has direct activity as a
reducing agent, chemically reacting with
reactive oxygen species to neutralize them.
[9] Based on lab studies, it appears that fisetin lodges in
cell membranes and prevents oxidative damage to
lipids in the cell membrane.
[9] Fisetin, like other flavonoids, has a planar structure, with multiple carbon rings. Fisetin is able to scavenge free radicals as a result of its electron donating capacity, which is due to the presence of two
hydroxyl groups on one ring and a hydroxyl group on another ring.
[9]
Disclosures and Disclaimers
WARNINGS: Although safe for children, this product should be kept out of the reach of children. Do not use if the packaging is open or damaged. As with any nutrient, if you are pregnant or breastfeeding, seek the advice of a health care provider before using this product.
Please know that this product can be taken safely by mouth. It is a dietary supplement in accordance with current FDA guidelines.
FOOD AND DRUG ADMINISTRATION (FDA) DISCLOSURE
*THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE.
Disclaimer: These statements have not been evaluated by the FDA. This product is a Federal Food, Drug, and Cosmetic Act compliant combination of naturally derived FDA GRAS (Generally regarded As Safe) herbal, nutraceutical, vitamins, minerals and amino acids products legally sold in the USA. In accordance with FDA regulations, with oral use it is a dietary supplement as defined by section 201(ff) of the Act, 21 U.S.C. § 321(ff). MitoZen’s product line is a naturally derived FDA GRAS (Generally regarded As Safe) mineral, herbal, vitamins and nutraceutical products which can be legally sold in the USA. ABC’s products are not a drug as defined in section 201(g)(1) of the Act, 21 U.S.C. § 321(g)(1). MitoZen’s products are not intended to affect the structure or function of the body and is not intended for use in the diagnosis, cure, mitigation, treatment or prevention of disease in man. Any nutritional suggestions and research regarding this product are provided for informational purposes only, and are not intended to diagnose, treat, cure or prevent disease nor should any information provided be used as a substitute for sound medical advice. This product is not for use by or sale to persons under the age of 18. This product should be used only as directed on the label. It should not be used if you are pregnant or nursing. Consult with a physician before use, if you have a serious medical condition or use prescription medications. A Doctor’s advice should be sought before using this and any supplemental dietary product. All trademarks and copyrights are the property of their respective owners, and are not affiliated with nor do they endorse this product. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. By using this site you agree to follow the Privacy Policy and Terms & Conditions printed on this site. Void Where Prohibited By Law.
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