Lucitol™ Ultra (Polyphenol Liposomal)
$139.95 – $499.95
Lucitol™ is a product that was developed with much excitement and care to make sure the blend was perfect. We spent many months working with various plant polyphenol’s from the flavonoid group. Lucitol™ Suppositories are designed to provide the cleanest and most complete absorption of these key nutrients. This all star line up of Fisetin, Resveritrol, Ginko B., EGCG, Lutein, Quercitin & Curcumin are all in the Lucitol™ suppository. Also see NeuroNAD™ suppository. Fasting is also a great way to clean up cellular senescence, and Lucitol™ suppository can be taken safely during a fast. Polyphenols such as Fisetin & Curcumin are poorly absorbed through oral ingestion. Suppositories offer a valuable means to receive the most potent and fullest potential of these nutrients.
Lucitol Ultra™ is a product that was developed with much excitement and care, to make sure the blend was perfect. We spent many months working with various plant polyphenol’s from the flavonoid group. Lucitol Ultra™ is designed to provide the cleanest and most complete absorption of these key nutrients. This all star line up of Fisetin, Resveritrol, Ginko B., EGCG, Lutein, Quercitin & Curcumin are all in the Lucitol Ultra™. Also see NADMax Ultra™. Fasting is also a great way to clean up cellular senescence! Lucitol Ultra™ can be take safely during a fast, as well as after using NAD+ Products, to minimize senescent survivability. Polyphenols such as Fisetin & Curcumin are poorly absorbed through oral ingestion. Liposomes offer a valuable means to receive the most potent and fullest potential of these nutrients.
Liposomal delivery systems, with their advanced nutrient bioavailability, are becoming more popular. There are over 65,000 peer reviewed published studies on Liposomal delivery. They are utilized in medicine for the delivery of vaccines, hormones, enzymes, vitamins and botanicals.
Liposomes are tiny lipid bubbles about the width of a single human hair. They are made out of the same type of fat as our own cell membranes called phospholipids. Liposomes are stable, and can carry both water and fat-soluble nutrients. When formulated correctly, they can facilitate absorption as soon as they land on the tongue, and can help protect breakdown by digestive acids, enzymes and first pass thtrough the liver. Because they are made of the same lipids that compose our own cell membranes, they may assist nutrients to gain access into the cell membrane and optimize cellular support.
Liposomal technology like suppository has been said to provide the power of intravenous therapy. Because of enhanced delivery and absorption, nutrients delivered in liposomal form at lower doses may offer equal or greater efficacy than higher doses provided in forms that are less bioavailable.,
Their potency is impressive. In liposomal form, the absorption of glutathione can compare to that of intravenous formulations, and appears to help maintain intracellular storage., Even better, the phospholipids in liposomes are therapeutic. They help nourish every cell membrane by providing the lipids needed to function optimally and flush out toxins that accumulate there.
Advanced Ultra-Nano Liposomal Formulations Are More Effective
Not all liposomes are alike. The technology used to manufacture them, as well as their size, can vary considerably.
Liposomes are emulsions, but not all emulsions can become a liposomes. Liposomes are specific ‘vesicles’ or bubbles modified to carry either fat-soluble or water soluble molecules. Their likeness to living bi-layer lipid cell membranes is remarkable. If a vitamin or nutrient is placed inside the liposome, it will not readily pass through the bilayer. When the liposome merges with the lipid bilayer of the cell membrane, it can deliver its contents directly to the cell.
The size of a liposome—smaller sizes have been shown to offer dramatically higher uptake such as with our Ultra-Nano. That’s because the tiniest vesicles can be dramatically more efficient at cellular delivery of encapsulated nutraceuticals. In one notable study, cellular uptake increased 9-fold as liposome size dropped from 236 nm to 97 nm. At the smallest size of 64 nm, the uptake was 34-fold higher.
Beyond Liposomes: Ultra-Nano
Particles at this incredibly tiny size are so small that they are even smaller than wavelengths of visible light. They are crafted using modern technology and high level equipment.
Olthof MR, Hollman PC, et al. Bioavailabilities of quercetin-3-glucoside and quercetin-4′-glucoside do not differ in humans. J Nutr, 2000 May;130(5):1200-3. View Abstract
Seeram NP, Lee R, Heber D. Bioavailability of ellagic acid in human plasma after consumption of ellagitannins from pomegranate (Punica granatum L.) juice. Clin Chim Acta, 2004 Oct;348(1-2):63-8. View Abstract
Manach C, Williamson G, Morand C, et al. Bioavailability and bioefficacy of polyphenols in humans. Review of 97 bioavailability studies. Am J Clin Nutr, 2005 Jan;81(1 Suppl):230S-42S. View Abstract
Xu JZ, Yeung SY, Chang Q, et al. Comparison of antioxidant activity and bioavailability of tea epicatechins with their epimers. Br J Nutr, 2004 Jun;91(6):873-81. View Abstract
Nieves CJ, Montero C et al. Bioavailability of Herbs and Spices. The FASEB Journal 2009;23:1_supplement, 718.13 View Abstract
Emami S, Azadmard-Damirchi S et al. Liposomes as carrier vehicles for functional compounds in food sector, Journal of Experimental Nanoscience. 2016.11:9, 737-759. View Full Paper
 Taylor TM, Weiss J et al. Liposomal nanocapsules in food science and agriculture. Crit Rev Food Sci Nutr. 2005;45:587–605 View Full Paper
Silva AC, Santos D, et al. Lipid-based nanocarriers as an alternative for oral delivery of poorly water-soluble drugs: Peroral and mucosal routes. Curr Med Chem. 2012;19(26):4495-4510. View Abstract
Rogers JA, Anderson KE. The potential of liposomes in oral drug delivery. Crit Rev Ther Drug Carrier Syst. 1998;15(5):421-480. View Abstract
Levitskaia TG, Morris JE. Aminothiol receptors for decorporation of intravenously administered (60)Co in the rat. Health Phys. 2010 Jan;98(1):53-60. View Full Paper
Zeevalk GD, Bernard LP Liposomal-glutathione provides maintenance of intracellular glutathione and neuroprotection in mesencephalic neuronal cells. Neurochem Res. 2010 Oct;35(10):1575-87. View Abstract
 Unpublished study on Caco-2 intestinal cells by Quicksilver Scientific,
 Hood RR, Andar A, et al. Pharmacy-on-a-chip: Microfluidic synthesis of pegylated and folate receptor-targeted liposomes for drug delivery. 16th International Conference on Miniaturized Systems for Chemistry and Life Sciencies. 2012. Okinawa, Japan.
Alexander-Bryant AA, Wen X. Bioengineering Strategies for Designing Targeted Cancer Therapies. In: Advances in Cancer Research, 2013 View Abstract
Smith ME, Morton DG. Digestion And Absorption. In: The Digestive System (Second Edition), 2010
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Kedar U et al. Advances in polymeric micelles for drug delivery and tumor targeting. Nanomedicine, 6 (6) (2010), pp. 714-729
Shoji Y, Nakashima H. Nutraceutics and delivery systems. J Drug Target, 2004;12(6):385-91.
Dosage and Storage Instructions: Suggested dosage is 1 (one) suppository daily or 3 times a week. Depending on your daily schedule. Consider taking Lucitol™ during and after fasting as well as when taking NAD+ Products to minimize senescent survivability.
Product is not intended for oral usage. Store this product in a refrigerated climate. Keep this product away from sunlight. Please use the product within six months of purchase date for best results.
Serving size: 1 Servings: 12 Amount Per Serving % Daily Value
Fisetin, Ginko B., EGCG, Lutein *****
Quercitin, Curcumin. *****
Organic Orange & Vanilla Essential Oil *****
SRT Polysaccharide Complex. *****
Organic Sunflower Lethicin. *****.
Stevia , Erythritol. *****
****Daily Value not established****
ResearchSome of the most exciting studies on these polyphenols in neurology, as well as (senolytic/autophagy) and to address microglial activation. See the amazing studies on Fisetin (Ref) you will see why many are looking at this nutrients as the father of all anti aging substances. Take a close look at Micro Glial activation as well as Cellular senescence to fully appreciate Lucitol™ (Ref). Senescent cells accumulate with age! Senescent cells are cells that go into a permanent state of sleep like a zombie and continue to consume energy and product lots of oxidation! Senescent cells secrete pro-inflammatory chemicals form something scientist call SASP (senescence-associated secretory phenotype). The SASP’s is thought to significantly contribute to aging! (Ref) Senolytics which remove SASP’s are a great strategy for promoting health and longevity. Poor energy levels at a cellular level are a headwind for the body to properly clear out these zombie cells. Mitochondria, the power house of the cell, it a key component to this cellular energy. Both NAD+ as well as mitochondria health decline with age. Fisetin, Resveritrol, Ginko B., EGCG, Lutein, Quercitin & Curcumin are all heavlily researched. Also Fasting is also a great way to clean up cellular senescence! Freund, A., Orjalo, A. V., Desprez, P. Y., & Campisi, J. (2010). Inflammatory networks during cellular senescence: causes and consequences. Trends in molecular medicine, 16(5), 238-246.  Coppé, J. P., Desprez, P. Y., Krtolica, A., & Campisi, J. (2010). The senescence-associated secretory phenotype: the dark side of tumor suppression. Annual review of pathology, 5, 99. Fisetin, like other polyphenols such as resveratrol, is a sirtuin-activating compound and has been shown in laboratory studies to extend the life of simple organisms like yeast, worms, and flies. Like the other compounds, it has also been shown to be reactive in many different assays of biological activities, raising the possibility that any drug generated from fisetin would have too many side effects to be useful. Fisetin has shown anti-cancer activity in studies on cells and model animals conducted in laboratories, and appears to block the PI3K/AKT/mTOR pathway. In lab studies it also has been shown to be an anti-proliferative agent, interfering with the cell cycle in several ways.Fisetin, like some other flavonoids, has been found in lab studies to be a topoisomerase inhibitor, which may turn out to be a carcinogenic activity or an anti-cancer activity – further research is needed. Fisetin has been shown to be an effective senolytic agent in wild-type mice, with effects of increased lifespan, reduced senescence markers in tissues, and reduced age-related pathologies. A clinical trial in the U.S. is currently underway as of October 2018 to show effectiveness in humans. In studies conducted on cells in a laboratory, fisetin inhibits the activity of several pro-inflammatory cytokines, including tumor necrosis factor alpha, interleukin 6, and Nuclear factor kappa B. It has also been shown in lab studies to upregulate glutathione, an endogenous antioxidant. Fisetin also has direct activity as a reducing agent, chemically reacting with reactive oxygen species to neutralize them. Based on lab studies, it appears that fisetin lodges in cell membranes and prevents oxidative damage to lipids in the cell membrane. Fisetin, like other flavonoids, has a planar structure, with multiple carbon rings. Fisetin is able to scavenge free radicals as a result of its electron donating capacity, which is due to the presence of two hydroxyl groups on one ring and a hydroxyl group on another ring.
Disclosures and Disclaimers
Disclosures and Disclaimers
Advanced Biome Corp does not sell or distribute any products that are in violation of the United States Controlled Substances Act (USA CDA). The company does sell and distribute hemp-based products.
FOOD AND DRUG ADMINISTRATION (FDA) DISCLOSURE
The statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent disease or medical conditions. The products and information found on AdvancedBiomeCorp.com are not intended to replace professional medical advice or treatment. Individual results may vary. Advanced Biome Corp urges you to seek the advice of a qualified professional for any health concern, and to share with your provider any information pertaining to your health and well-being, including the use of supplemental nutrition. We try our best not to make mistakes; however, if typographical errors appear in our site, we cannot be held responsible. All information presented here is not meant as a substitute for or alternative to information from healthcare practitioners. Please consult your healthcare professional about potential interactions or other complications before using any product. The Federal Food, Drug, and Cosmetic Act require this notice.
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Shipping & Delivery
During the hot summer months, we recommend taking advantage of the cold shipping option to ensure product stability upon arrival.
- Orders placed on a Thursday or Friday and requiring cold shipping will not ship until the following Monday.
- Orders placed over the weekend will not be shipped until Monday.
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