Testimonials

“I’m one of those guys who often takes oral supplements and notices next to nothing. That’s not uncommon. Digestion, pass through the liver, the acidic nature of the stomach and a host of other factors can keep you from properly absorbing precious molecules. But when I tried Dr. Lieurance’s nasal sprays and suppositories I noticed them almost immediately. I have now used them successfully for jet lag, inflammation and enhanced sleep and I’m completely enamored: these things are the real deal – and a valuable arsenal to any health hacker’s toolkit.”

Ben Greenfield

Dosage and Storage Instructions

Dosage and Storage Instructions:  To start, we recommend one serving of 20mg to 25mg of NeuroDiol™ Tincture per day. (See below for dosage for various strength’s NeuroDiol™ Tincture) Fill the dropper with 20-25 mg of oil & drop the amount of drops under the tongue. Allow the oil to absorb for 30-90 seconds. NeuroDiol™ Tincture can also be mixed with food or drink as desired. NeuroDiol™ Tincture absorbs best along with a fatty meal or a snack, such as a few macadamia nuts.

Take note of how your body has adapted to the NeuroDiol™ Tincture on a weekly basis and adjust your dosage based on your desired effect. Different people have various dosage requirements, so some people will require much higher dosage then others. Higher dosages are generally used for sleep, anxiety and pain control. Some protocols for autoimmune and significant sleep disorders can even range into the 100-300mg / day range. For best results, we encourage you to stick with the same NeuroDiol™ Tincture routine for 30 days, or consult your health care provider for direction.

Product is intended for oral usage.

Keep this product away from sunlight. Please use the product within six months of purchase date for best results.

There are 600 drops in each 30 mil bottle and 200 drops in the 10 ml bottle.

NeuroDiol™ Tincture 1,500.                          2.5mg   / drop — 8-10 drops = 20mg-25mg CBD

NeuroDiol™ Tincture 2,500.                       4.17mg /drop –8-10 drops  = 33.4mg-42mg CBD

NeuroDiol™ Tincture 5,000                     8.33mg / drop 8-10 drops  =  67mg – 83mg CBD

NeuroDiol™ Tincture 5,000 (10ml)          25mg  /  drop  2-4 drops  = 50mg-100mg CBD

NeuroDiol™ Tincture includes terpenes and MCT oil for better absorption than any other CBD tincture on the market. NeuroDiol™ offers Topical Cream, Suppository and Nasal Spray, which all bypass the first pass liver effect for faster onsets.

Tips and Tricks

Terpene Profile

Terpenes: These are the NON psychoactive components in cannabis. They are the fragrant essence of ALL essential oils! They give plants their unique smell and they also hold the healing benefits within the plants. Terpenes have been studied extensively and are at the forefront of interest of the pharmaceutical companies, due to the unique and safe profile they can have. Terpenes specifically shown to reduce pain,  and are anti inflammatory as well as reduce anxiety, have been incorporated into NeuroDiol™.* These terpenes have been shown to improve CBD and other cannabinoids utilization, as well as uptake into the brain.*

Myrcene: is a terpene that occurs often in highly fragrant plants and herbs such as mangoes, hops, bay laurel leaves, thyme, lemongrass, and basil. Myrcene is produced by numerous cannabis strains, and some rodent-model studies have suggested that it might lend sedative effects. Main effects are Anti-inflammatory, Analgesic (pain relief), Antibiotic and Mood Elevation.*

Another place you’ll find myrcene is in mangoes. Anecdotal evidence suggests that eating a ripe mango prior to consuming cannabis may accentuate or extend the effects of cannabinoids; some have suggested that this is due to the fruit’s concentrations of myrcene, which is naturally synergistic with CBD and allows cannabinoids to more easily bridge the blood-brain barrier.

Limonene: is an aromatic cannabis terpene produced in the flower’s resin glands. In isolation, it’s commonly associated with fruity and citrus aromas. Inhalation of limonene vapor increases serotonin and dopamine levels in key regions of the brain that are associated with anxiety, depression, and OCD. Limonene’s potential therapeutic benefits have shown potential in the following applications: Elevated mood*, Stress relief*, Antifungal properties*, Antibacterial properties*, May help relieve heartburn and gastric reflux*, Improves absorption of other terpenes and chemicals by way of the skin, mucous membranes, and digestive tract* (Ref)

Alpha & Beta Pinene, as you might have guessed it, has a strong scent of pine. Commonly found in conifer trees, parsley, dill, basil, and rosemary, alpha-pinene is easy to detect.

A study in 2012 showed that alpha-pinene was a potent anti-inflammatory agent against Acute Pancreatitis, an inflammatory disease with an unknown cause. A study in 2011 showed that alpha-pinene, along with all the different cannabinoids and terpenes found in cannabis, interact synergistically and amplify anti-inflammatory activity. These results show that alpha-pinene support lower inflammation management for diseases such as arthritis, Crohn’s, and multiple sclerosis.*

Both alpha-pinene and beta-pinene proved to be effective antimicrobial agents against bacterial and fungal cells. In 2011, alpha-pinene was tested as a potent treatment against a bronchitis virus that was previously hard to treat since antibiotics don’t work on viruses. Although not effective against all bacteria and viruses, alpha-pinene was shown in research to support the immune system with a wide range of these infectious diseases. More studies need to be performed to assess the effectiveness of alpha-pinene on all bacteria. (Ref)

Bronchodilator: In a 2011 study, alpha-pinene showed promise as a bronchodilator by opening up the upper respiratory tract (at low exposure levels), which can be helpful for people with asthma.

Memory: We’ve all heard of the forgetful stoner stereotype. The cannabinoid tetrahydrocannabinol (THC) plays a part in decreasing short-term memory attention. The alpha-pinene terpene, however, has been shown to counteract these memory impairing effects. Alpha-pinene plays a strong role in inhibiting acetylcholinesterase activity in the brain, which helps you retain memories more efficiently. (Ref)

Alpha Phellandrene: This terpene smells herbaceous, citrusy, minty, peppery, and a little woodsy. The next time you smell mint leaves or a lavender candle, appreciate the Alpha Phellandrene terpene smell!

Anti-depressive & Analgesic Actions of limonene, α-Phellandrene, and in a Neuropathic Pain Model (Ref)

Alpha–phellandrene significantly inhibited the production of the pro-inflammatory cytokines TNF-α and IL-6. Alpha–phellandrene Promotes Immune Responses in Normal Mice Through Enhancing Macrophage Phagocytosis and Natural Killer Cell Activities.  (Ref)

Alpha–phellandrene has modulating effect on neutrophil migration and mast cell degranulation processes. (Ref)

Boswellia: or Indian frankincense, is a resin herbal extract from the boswellia tree, which natural medicine practices have used for centuries. Its anti-inflammatory effects mean that it may help with inflammatory conditions, such as rheumatoid arthritis, inflammatory bowel disease, and asthma. We included this amazing extract into our products, due to all of the positive healing properties

Linalool: is a naturally occurring terpene found in many flowers and spices including lavender and coriander. It gives off a complex yet delicate floral aroma, and while its effects are myriad, it is in particular one of the substances used most widely to reduce stress. Humans have inhaled the scent of certain plants, including many containing linalool, since ancient times to help lower stress levels, fight inflammation, and combat depression.* Linalool has been the subject of many studies, including a recent one in which scientists allowed lab rats to inhale linalool while exposing them to stressful conditions. It was reported that linalool returned elevated stress levels in the immune system to near-normal conditions. Linalool’s effects and benefits include anti-anxiety, antidepressant, mood elevation, anti-inflammatory, anti-epileptic and analgesic.* (Ref)

CBD research

CBD research under review:
Many studies on the impact of CBD, Hemp, Terpenes and Cannabis have historically employed small sample sizes, which limits the data researchers can gather and the conclusions they can draw from it. As the volume of these studies grows, though larger studies there will be more data to conduct review studies on the effects and efficacy of cannabis and its components, including CBD and Terpenes.

Rather than conducting a new experiment, review studies collate and compare the results of previously published, peer-reviewed studies. This allows authors to work with what is effectively a larger data set and more confidently answer questions about the subject.

Disclosures, COA's & Analytics

Advanced Biome Corp does not sell or distribute any products that are in violation of the United States Controlled Substances Act (USA CDA). The company does sell and distribute hemp-based products.

FOOD AND DRUG ADMINISTRATION (FDA) DISCLOSURE

The statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent disease or medical conditions. The products and information found on AdvancedBiomeCorp.com are not intended to replace professional medical advice or treatment. Individual results may vary. Advanced Biome Corp urges you to seek the advice of a qualified professional for any health concern, and to share with your provider any information pertaining to your health and well-being, including the use of supplemental nutrition. We try our best not to make mistakes; however, if typographical errors appear in our site, we cannot be held responsible. All information presented here is not meant as a substitute for, or alternative to, information from healthcare practitioners. Please consult your healthcare professional about potential interactions or other complications before using any product. The Federal Food, Drug, and Cosmetic Act require this notice.

COA’s and Lab Testing